Explicit interaction information from WikiPathways in RDF facilitates drug discovery in the Open PHACTS Discovery
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چکیده
Open PHACTS is a pre-competitive project to answer scientific questions developed recently by the pharmaceutical industry. Having high quality biological interaction information in the Open PHACTS Discovery Platform is needed to answer multiple pathway related questions. To address this, updated WikiPathways data has been added to the platform. This data includes information about biological interactions, such as stimulation and inhibition. The platform's Application Programming Interface (API) was extended with appropriate calls to reference these interactions. These new methods of the Open PHACTS API are available now. Ryan A. Miller ( ) Corresponding author: [email protected] : Writing – Original Draft Preparation; : Conceptualization; : Conceptualization, Software, Author roles: A. Miller R Woollard P L. Willighagen E Supervision; : Data Curation; : Conceptualization; : Software; : Conceptualization; : Digles D Kutmon M Loizou A Waagmeester A Senger S Conceptualization; : Conceptualization, Supervision Evelo CT No competing interests were disclosed. Competing interests: A. Miller R, Woollard P, L. Willighagen E How to cite this article: et al. Explicit interaction information from WikiPathways in RDF facilitates 2018, :75 (doi: drug discovery in the Open PHACTS Discovery Platform [version 1; referees: awaiting peer review] F1000Research 7 ) 10.12688/f1000research.13197.1 © 2018 A. Miller R . This is an open access article distributed under the terms of the , which Copyright: et al Creative Commons Attribution Licence permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This work was supported by the Innovative Medicines Initiative Joint Undertaking [115191], resources of which are composed Grant information: of financial contribution from the European Union’s Seventh FrameworkProgramme (FP7/2007-2013) and EFPIA companies’ in kind contribution. 17 Jan 2018, :75 (doi: ) First published: 7 10.12688/f1000research.13197.1 1 2 1 3
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Explicit interaction information from WikiPathways in RDF facilitates drug discovery in the Open PHACTS Discovery
Open PHACTS is a pre-competitive project to answer scientific questions developed recently by the pharmaceutical industry. Having high quality biological interaction information in the Open PHACTS Discovery Platform is needed to answer multiple pathway related questions. To address this, updated WikiPathways data has been added to the platform. This data includes information about biological in...
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